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产品型号:UA040135
更新时间:2025-08-11
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蛋白
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Tumor Necrosis Factor alpha (TNF-α), is an inflammatorycytokine produced by macrophages/monocytes during acute inflammation and isresponsible for a diverse range of signaling events within cells, leading tonecrosis or apoptosis. TNF-α exerts many of its effects by binding to either a55 kDa cell membrane receptor termed. TNF-α activates signals through tworeceptors, TNF-R1, which is expressed on most cell types, and TNF-R2, which isexpressed mainly on immune cells. TNF-α can have many functions including, tostimulate of phagocytosis in macrophages, to chemoattract neutrophils, toincrease insulin resistance and to induce fever.
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