VEGF-121 Protein, Human

产品型号：UA040082

更新时间：2025-08-11

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产品介绍

VEGF-121, an abundant splicing isoform of vascular endothelial growth factor （VEGF）, exists as a disulfide-linked homodimer. It induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Contrast to other isoforms, VEGF-121 has very little affinity for heparin-sulfate proteoglycans, without recruiting Neuropilin1-expressing monocytes （NEMs）, conferring to VEGF-121 the ability to diffuse freely, and increase tumor growth rate in vivo.

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