DT3C (Diphtheria toxin & spg 3C domain) Protein, Corynephage beta

产品型号：UA070063

更新时间：2025-08-11

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蛋白

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产品介绍

DT3C consists of diphtheria toxin （DT） lacking the receptor-binding domain but containing the C1, C2, and C3 domains of Streptococcus protein G （3C）. When a mAb–DT3C conjugate, which functions in vitro like an ADC, reduces the viability of cancer cells, the mAb being tested must have been internalized by the target cells. DT3C can thus be a tool to identify efficiently and easily mAbs that can be internalized by cells, thereby enhancing the development of promising ADCs.

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