13774214275
13774214275
产品中心
产品型号：S0B3222
更新时间：2025-08-06
厂商性质：生产厂家
访问量：40
服务热线15855403091
HbA1c is a glycated protein in which glucose binds with N-terminal valine residue in the β chain of hemoglobin nonenzymatically. Glycated protein is produced by the two-step nonenzymatic reaction called the Maillard early-phase reaction. First, the free amino group of protein and the aldehyde group of glucose form the Schiff base, which produces a substance called aldimine. This reaction is relatively quick and reversible. Then, this aldimine becomes ketoamine by the Amadori rearrangement reaction, leading to the production of stable Amadori product, that is, glycated protein. This reaction progresses slowly and is almost irreversible. Since the speed of production of glycated protein is proportional to the plasma glucose level, the glycation rate of protein is proportional to the plasma glucose level at the time of production. As HbA1c is produced slowly corresponding to the plasma glucose levels and survives for about 120 days, the life-span of red blood cells, it is an excellent index for long-term glycemic control.
当前位置：
上一个：
返回列表
