13774214275
13774214275
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产品型号：S0B1821
更新时间：2025-08-07
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CD27 is a transmembrane protein that belongs to the tumor necrosis factor receptor superfamily （TNFRSF） and is primarily expressed on T cells, B cells, and natural killer （NK） cells. It activates NF-κB and JNK signaling pathways by binding to its ligand, CD70, thereby promoting the activation, proliferation, and differentiation of T cells. CD27 plays a crucial role in immune regulation, acting as an important co-stimulatory receptor for T and B cells, and is involved in modulating immune responses and the formation of memory cells. Additionally, CD27 is being studied as a potential target for anti-tumor immunotherapy.
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