13774214275
13774214275
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产品型号：S0B5041
更新时间：2025-08-07
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The TCR delta chain is a crucial component of the γδ T cell receptor （TCR）, forming a heterodimer with the TCR gamma chain. This TCRγδ complex is primarily expressed on the surface of γδ T cells and is capable of recognizing a diverse range of antigens, including non-peptide small molecules and glycolipids. Unlike αβ T cells, the TCR delta chain generates diversity through V（D）J recombination, but it has a relatively small gene repertoire and lacks the capacity for somatic hypermutation. The TCRγδ complex associates with the CD3 complex to form an octameric structure, which is involved in T cell activation and signaling. γδ T cells possess both adaptive and innate immune characteristics, allowing them to rapidly respond to pathogen infections, tumor growth, and tissue damage.
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