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APC Rat Anti-Mouse CD19 Antibody (S-R532)
产品简介:

APC Rat Anti-Mouse CD19 Antibody (S-R532)

产品型号:S0B5448

更新时间:2025-08-08

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产品介绍

CD19 is a 95 kDa type I transmembrane glycoprotein that belongs to the immunoglobulin superfamily and is expressed on the surface of B lymphocytes and follicular dendritic cells. It plays a crucial role in B cell activation and humoral immune responses by forming a complex with CD21, CD81, and CD225. This complex reduces the threshold for B cell receptor (BCR) activation, enhancing downstream signaling pathways and facilitating B cell responses to antigens. CD19 is also a biomarker for B cell development and lymphoma diagnosis, and it is targeted in immunotherapies for diseases like leukemia.

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