13774214275
13774214275
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产品型号：S0B5506
更新时间：2025-08-08
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The CD68 protein is a heavily glycosylated transmembrane protein belonging to the lysosome-associated membrane glycoprotein （LAMP） family, primarily serving as a macrophage marker. With a molecular weight of approximately 110 kDa, it contains scavenger receptor-like cysteine-rich domains and participates in innate immune responses by binding specific ligands such as oxidized low-density lipoprotein （oxLDL）. Localized to lysosomal and endosomal membranes, CD68 plays a crucial role in antigen presentation, inflammatory responses, and tissue repair. It is commonly detected via immunohistochemistry （e.g., using the PG-M1 antibody） and is widely utilized to identify tumor-associated macrophages （TAMs） and assess pathological progression in chronic inflammatory diseases, including atherosclerosis and rheumatoid arthritis.
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