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LDL receptor Recombinant Rabbit mAb (SDT-057-57)
产品简介:

LDL receptor Recombinant Rabbit mAb (SDT-057-57)

产品型号:S0B2054

更新时间:2025-08-08

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产品介绍

The low density lipoprotein receptor (LDL R) is the founding member of the LDL R family of scavenger receptors.Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis.LDLR is ubiquitously expressed and is a key receptor for maintaining cholesterol homeostasis in mammals. LDLR-mediated endocytosis is essential for lipoprotein and lipid metabolism.Impaired LDLR function by genetic mutations results in a condition with extremely elevated serum LDL levels and early onset atherosclerosis known as familial hypercholesterolemia (FH).

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