CD278/ICOS Recombinant Rabbit mAb (SDT-R104)

产品型号：S0B2154

更新时间：2025-08-08

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抗体/抗原

ELISA试剂盒抗体试剂盒二抗试剂盒二抗其它流式抗体琼脂糖/磁珠偶联抗体抗Payload抗体泛修饰抗体标签/内参抗体功能性抗体 Biosimilar抗体偶联抗体配对抗体病理/IHC抗体

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产品介绍

Inducible T cell costimulatory factor （ICOS, cluster of differentiation, CD278） is an activated costimulatory immune checkpoint expressed on T cells. Its ligand ICOSL was expressed in antigen-presenting cells and somatic cells （including tumor cells in the tumor microenvironment） [PMID: 28713380, PMID: 12800259]. As one of the most common targeted immune checkpoints, ICOS is considered a possible way to develop new immunotherapy [PMID: 29544515]. Some clinical studies shown that blocking ICOS alone can inhibit tumor growth and proliferation, as well as TIGIT, CTLA4, and PD-1 [PMID: 30232519, PMID: 28803728].

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