Androgen Receptor Recombinant Rabbit mAb (SDT-R157)

产品型号：S0B2180

更新时间：2025-08-08

厂商性质：生产厂家

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抗体/抗原

ELISA试剂盒抗体试剂盒二抗试剂盒二抗其它流式抗体琼脂糖/磁珠偶联抗体抗Payload抗体泛修饰抗体标签/内参抗体功能性抗体 Biosimilar抗体偶联抗体配对抗体病理/IHC抗体

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产品介绍

The androgen receptor （AR）, ligand-induced transcription factor, is expressed in primary prostate cancer and in metastases. AR regulates multiple cellular events, proliferation, apoptosis, migration, invasion, and differentiation. Its expression in prostate cancer cells is regulated by steroid and peptide hormones [PMID: 24384911]. The elucidation of the structures of the AR DNA binding domain （DBD） and ligand binding domain （LBD） provides a new framework for understanding the functions of this receptor and leads to the development of rational drug design for the treatment of prostate cancer [PMID: 24909511].

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