Alexa Fluor? 488 Mouse Anti-Human CD184 Antibody (S-R635)

产品型号：S0B5275

更新时间：2025-08-07

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抗体/抗原

ELISA试剂盒抗体试剂盒二抗试剂盒二抗其它流式抗体琼脂糖/磁珠偶联抗体抗Payload抗体泛修饰抗体标签/内参抗体功能性抗体 Biosimilar抗体偶联抗体配对抗体病理/IHC抗体

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产品介绍

CD184, also known as CXCR4 or fusin, is a 45 kD seven-transmembrane G-protein-linked CXC chemokine receptor. It is widely expressed on various human cells, including leukocytes, hematopoietic stem cells, epithelial cells, endothelial cells, and cancer cells. This receptor is specific for stromal-derived factor-1 （SDF-1, also called CXCL12） and plays a crucial role in cell migration, hematopoiesis, cell homing, and the proliferation of non-hematopoietic cells. Additionally, CXCR4 serves as a co-receptor for T-cell tropic HIV viruses, enabling their entry into human lymphocytes. In cancer, CXCR4 is involved in tumor cell survival, proliferation, migration, and metastasis, making it a potential therapeutic target.

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