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更新时间:2025-08-08
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Caldesmon is a binding protein of smooth actin and calmodulin, a cytoskeleton-associated protein present in thin filaments (smooth and striated muscles) that regulates the interaction of actin and myosin. It is available in low molecular weight (l-Caldesmon) and high molecular weight (h-Caldesmon). The latter is thought to be present only in visceral and vascular smooth muscle and myoepithelium. Caldesmon is commonly used in the diagnosis of smooth muscle differentiation tumors.