B7-H4 Recombinant Rabbit mAb (SDT-314-447-2)

产品型号：S0B2235

更新时间：2025-08-08

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抗体/抗原

ELISA试剂盒抗体试剂盒二抗试剂盒二抗其它流式抗体琼脂糖/磁珠偶联抗体抗Payload抗体泛修饰抗体标签/内参抗体功能性抗体 Biosimilar抗体偶联抗体配对抗体病理/IHC抗体

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产品介绍

B7-H4 is a transmembrane protein that binds an unknown receptor on activated T cells resulting in inhibition of T-cell effector function via cell cycle arrest, decreased proliferation, and reduced IL-2 production. B7-H4 is up-regulated on the surface of cancer cells and immunosuppressive tumor-associated macrophages （TAMs） in a variety of human cancers. Notably, B7-H4 expression levels inversely correlate with patient survival in ovarian cancer, cholangiocarcinoma, breast cancer and endometrial cancer, making B7-H4 an attractive candidate for therapeutic intervention.

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