Histone H3 Recombinant Rabbit mAb (Alexa Fluor? 647 Conjugate) (S-266-44)

产品型号：S0B1522

更新时间：2025-08-09

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抗体/抗原

ELISA试剂盒抗体试剂盒二抗试剂盒二抗其它流式抗体琼脂糖/磁珠偶联抗体抗Payload抗体泛修饰抗体标签/内参抗体功能性抗体 Biosimilar抗体偶联抗体配对抗体病理/IHC抗体

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产品介绍

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. H3.1 is enriched in PTMs associated with gene activation （K14 acetylation） and gene silencing （K9 dimethylation）, suggesting that these mammalian H3 variants may, indeed, have separate biological functions.

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