Lamin B1 Recombinant Rabbit mAb (Alexa Fluor? 488 Conjugate) (SDT-307-108)

产品型号：S0B1735

更新时间：2025-08-10

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抗体/抗原

ELISA试剂盒抗体试剂盒二抗试剂盒二抗其它流式抗体琼脂糖/磁珠偶联抗体抗Payload抗体泛修饰抗体标签/内参抗体功能性抗体 Biosimilar抗体偶联抗体配对抗体病理/IHC抗体

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产品介绍

Lamin-B1 is a protein that in humans is encoded by the LMNB1 gene. It is one of the essential members of the nuclear lamina protein family. Its main function is to maintain the integrity of nuclear skeleton, as well as to participate in the cell proliferation and aging by affecting the chromosome distribution. gene expression, and DNA damage repair. The abnormal expression of lamin B1 is related to certain diseases, including neurological diseases [e.g. neural tube defects （NDTs）, adult-onset autosomal dominant leukodystrophy （ADLD）] and tumors （e.g. pancreatic cancer）. It is also a potential tumor marker as well as drug target.

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