p27 Recombinant Rabbit mAb (Alexa Fluor? 700 Conjugate) (SDT-361-324)

产品型号：S0B1768

更新时间：2025-08-10

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抗体/抗原

ELISA试剂盒抗体试剂盒二抗试剂盒二抗其它流式抗体琼脂糖/磁珠偶联抗体抗Payload抗体泛修饰抗体标签/内参抗体功能性抗体 Biosimilar抗体偶联抗体配对抗体病理/IHC抗体

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产品介绍

p27 KIP1 is a member of the Cyclin Inhibitory Protein/Kinase Inhibitory Protein （CIP/KIP） family of cyclin-dependent kinase （Cdk） inhibitors. It plays roles in all phases of the cell division cycle. Its inhibitory binding to CDK2/cyclin E and other CDK/cyclin complexes enforces the G1 restriction point. Thus, important cellular functions as the cell division cycle, respiration, RNA processing, translation, and cell adhesion, are under p27 KIP1 regulation. Loss or reduced expression is associated with poor outcome in carcinoma of breast, prostate, GI tract and lung.

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