13774214275
13774214275
产品中心
产品型号：S0B0923
更新时间：2025-08-06
厂商性质：生产厂家
访问量：47
服务热线15855403091
相关文章
CD28 is a key costimulatory receptor predominantly expressed on T cells, which plays an essential role in T cell activation, proliferation, and survival. Upon binding to its ligands CD80 （B7-1） and CD86 （B7-2） expressed on antigen-presenting cells, CD28 provides a secondary signal that amplifies the initial T cell receptor engagement with the antigen. This costimulation is crucial for preventing T cell anergy and for the full execution of immune responses, including the production of cytokines and the development of memory T cells. CD28 also contributes to the induction and maintenance of regulatory T cells, and its signaling involves the activation of multiple downstream pathways, including the PI3K-AKT axis, which is important for cell metabolism and survival.
当前位置：
上一个：
返回列表
