Armenian hamster Anti-Mouse CD194 Antibody (S-R694)

产品型号：S0B5169

更新时间：2025-08-07

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抗体/抗原

ELISA试剂盒抗体试剂盒二抗试剂盒二抗其它流式抗体琼脂糖/磁珠偶联抗体抗Payload抗体泛修饰抗体标签/内参抗体功能性抗体 Biosimilar抗体偶联抗体配对抗体病理/IHC抗体

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产品介绍

CD194, also known as CCR4 （C-C chemokine receptor type 4）, is a G protein-coupled receptor with seven transmembrane domains. It is expressed on various immune cells, including CD4+ T cells （especially Th2 cells）, regulatory T cells （Tregs）, basophils, monocytes, and natural killer （NK） cells. CCR4 binds to chemokines such as CCL17 （TARC） and CCL22 （MDC）, playing a crucial role in the recruitment of memory T cells and immune responses in conditions like atopic dermatitis and asthma. Additionally, CCR4 is involved in tumor biology, with high expression levels associated with tumor infiltration and prognosis in both hematological malignancies and solid tumors, making it a potential target for cancer immunotherapy.

上一个：S0B5170Biotin Rat Anti-Mouse CD105 Antibody (S-R529)