APC Rat Anti-Mouse/Human CD45R/B220 Antibody (S-R519)

产品型号：S0B5167

更新时间：2025-08-07

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抗体/抗原

ELISA试剂盒抗体试剂盒二抗试剂盒二抗其它流式抗体琼脂糖/磁珠偶联抗体抗Payload抗体泛修饰抗体标签/内参抗体功能性抗体 Biosimilar抗体偶联抗体配对抗体病理/IHC抗体

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产品介绍

CD45R/B220 is an isoform of the CD45 protein, a member of the protein tyrosine phosphatase （PTP） family, and serves as a critical regulator of T- and B-cell antigen receptor signaling. It is predominantly expressed on the surface of B cells, from early pro-B cells to mature and activated B cells, making it a commonly used pan-B cell marker in mice. Additionally, CD45R/B220 is also found on certain subsets of activated T cells, lymphokine-activated killer cells （LAK）, NK cell progenitors, and T cells in mutant mice. This molecule plays a crucial role in lymphocyte development and antigen signaling, and its expression is regulated during different stages of B cell maturation.

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