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更新时间:2025-10-08
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相关文章
CD24, also known as the cluster of differentiation 24, is a highly glycosylated glycosylphosphatidylinositol (GPI)-anchored surface protein that plays crucial roles in various physiological and pathological processes. Initially identified as a B-cell differentiation antigen, it is widely expressed in hematopoietic stem cells, B and T lymphocytes, epithelial cells, and neural cells. Structurally, CD24 has an intracellular domain, a transmembrane domain, and a heavily glycosylated extracellular domain, which is involved in cell adhesion, migration, differentiation, and apoptosis.